期刊
MAGNETIC RESONANCE IN MEDICINE
卷 48, 期 1, 页码 97-104出版社
WILEY
DOI: 10.1002/mrm.10198
关键词
in vivo; gastrocnemius; pennation; rat; DT-MRI
资金
- NIAMS NIH HHS [F32 AR08614] Funding Source: Medline
- NINDS NIH HHS [NS34834, R01 NS034834] Funding Source: Medline
Diffusion-tensor (DT) MRI fiber tracking may potentially be used for in vivo structural analysis. The purpose of this study was to assess quantitatively the ability of a DT-MRI fiber-tracking algorithm to measure the fiber orientation (pennation) in skeletal muscle in vivo. In five adult Sprague-Dawley rats, the pennation angle (theta) was measured in the rat lateral gastrocnemius with DT-MRI (theta(DT-mRI)) and by direct anatomical inspection (DAI) (theta(DAI)). The mean theta(DT-MRI) was not significantly different from the mean theta(DAI). In addition, the two methods were highly correlated (r = 0.89) and the regression of theta(DT-MRI) on theta(DAI) resulted in a slope not significantly different from 1 and an intercept not significantly different from zero. These data indicate that DT-MRI-based fiber tracking as implemented here is a valid tool for in vivo structural analysis of small-animal skeletal muscle, (C) 2002 Wiley-Liss, Inc.
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