期刊
FREE RADICAL BIOLOGY AND MEDICINE
卷 33, 期 1, 页码 142-148出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0891-5849(02)00871-7
关键词
procyanidin B2; (-)-epicatechin; absorption; urinary excretion; methylation; conjugation; degradation; antioxidant; rats; free radicals
We evaluated the bioavailability and plasma antioxidative activity after administration of procyanidin B2 [epicatechin-(4beta-8)-epicatechin] in rats. After procyanidin 132 administration, procyanidin B2 is absorbed and excreted in urine, and a portion of the PB2 is degraded to (-)-epicatechin and to the metabolized conjugated and/or methylated (-)-epicatechin internally in the rat. Moreover, PB2 reduces the accumulation of lipid peroxide in plasma oxidized by copper ions. (C) 2002 Elsevier Science Inc.
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