Cross-coupling reaction of organoboron compounds via base-assisted transmetalation to palladium(II) complexes

Until recently, organoboronic acids have been of limited use in organic synthesis due to their low reactivity for ionic reactions. During the past two decades; however, it has become increasingly clear that they are valuable reagents capable of undergoing many carbon-carbon bond formations in organic syntheses. In 1979, catalytic carbon-carbon bond formation, via transmetalation between organoboron compounds and palladium(II) halides, was found to proceed in the presence of a base. (C) 2002 Elsevier Science B.V. All rights reserved.