期刊
TRENDS IN GENETICS
卷 18, 期 7, 页码 335-337出版社
ELSEVIER SCIENCE LONDON
DOI: 10.1016/S0168-9525(02)02668-9
关键词
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A substantial fraction of hypothetical open reading frames (ORFs) in completely sequenced bacterial genomes are short, suggesting that many are not genes but random stretches of DNA. Although it is not feasible to authenticate the coding capacity of all such regions experimentally, comparisons of ORFs in related genomes can expose those that encode functional proteins.
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