期刊
JOURNAL OF NATURAL PRODUCTS
卷 65, 期 7, 页码 1033-1036出版社
AMER CHEMICAL SOC
DOI: 10.1021/np0106586
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Chemical investigation of the ethyl acetate extract of the Taiwanese Gorgonian coral Subergorgia suberosa has resulted in the, isolation of two new subergane-based sesquiterpenes, subergorgiol (1) and 2beta-acetoxysubergorgic acid (2), along with four known compounds, subergorgic acid methyl ester (3), 2beta-acetoxy methyl ester of subergorgic, acid (4), 2beta-hydroxysubergorgic acid (5), and subergorgic acid (6). The structures of the new metabolites 1 and 2 were determined on the basis of extensive spectral analyses. Subergorgiol (1) may be the biosynthetic precursor of 2-6. Compound 3 was found to exhibit moderate cytotoxicity against the growth of HeLa cancer cells.
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