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A practical and robust process to produce SB-214857, Lotrafiban, ((2S)-7-(4,4′-bipiperidinylcarbonyl)-2,3,4,5-tetrahydro-4-methyl-3-oxo-1H-1,4-benzodiazepine-2-acetic acid) utilising an enzymic resolution as the final step
ORGANIC PROCESS RESEARCH & DEVELOPMENT (2002)
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