期刊
JOURNAL OF CHROMATOGRAPHY A
卷 961, 期 2, 页码 171-193出版社
ELSEVIER
DOI: 10.1016/S0021-9673(02)00659-3
关键词
column selectivity; alkyl-silica columns; retention prediction; selectivity; stationary phases, LC
Retention factors k have been measured for 67 neutral, acidic and basic solutes of highly diverse molecular structure (size, shape, polarity, hydrogen bonding, pK(a), etc.) on 10 different C-18 columns (other conditions constant). These data have been combined with k values from a previous study (86 solutes, five different C-8 and C-18 columns) to develop a six-term equation for the correlation of retention as a function of solute and column. Values of k can be correlated with an accuracy of +/-1-2% (1 standard deviation). This suggests that all significant contributions to column selectivity have been identified (and can be measured) for individual alkyl-silica columns which do not have an embedded polar group. That is, columns of the latter kind can be quantitatively characterized in terms of selectivity for use in the separation of any sample. (C) 2002 Published by Elsevier Science B.V.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据