期刊
TETRAHEDRON LETTERS
卷 43, 期 29, 页码 5185-5187出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0040-4039(02)00971-1
关键词
organozinc reagents; Barbier reaction; C-alkylation of heterocycles
Pyrrole and indoles react smoothly with alkyl halides such as allyl bromide, prenyl bromide, crotyl bromide and propargyl bromide in the presence of zinc metal in THE to afford the corresponding 3- and 2-alkyl pyrrole and 3-alkyl indole derivatives in good yields with high regioselectivity. (C) 2002 Elsevier Science Ltd. All rights reserved.
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