Analgesic and anti-inflammatory effects of the aqueous extract of leaves of Persea americana Mill (Lauraceae)

The aqueous extract of Persea americana leaves produced a dose-dependent inhibition of both phases of formalin pain test in mice, a reduction in mouse writhing induced by acetic acid and an elevation of pain threshold in the hot plate test in mice. The extract also produced a dose-dependent inhibition of carrageenan-induced rat paw oedema. The results obtained indicate that the extract possesses analgesic and anti-inflammatory effects. (C) 2002 Elsevier Science B.V. All rights reserved.