期刊
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
卷 46, 期 8, 页码 2668-2670出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.46.8.2668-2670.2002
关键词
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资金
- NCI NIH HHS [CA 21765, P30 CA021765] Funding Source: Medline
Although the antimicrobial effects of silver salts were noticed long ago, the molecular mechanism of the bactericidal action of Ag+ in low concentrations has not been elucidated. Here, we show that low concentrations of Ag+ induce a massive proton leakage through the Vibrio cholerae membrane, which results in complete deenergization and, with a high degree of probability, cell death.
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