期刊
JOURNAL OF NEUROCHEMISTRY
卷 82, 期 4, 页码 736-754出版社
WILEY
DOI: 10.1046/j.1471-4159.2002.01041.x
关键词
affective disorder and treatment; diphosphoinositol polyphosphates; inositol hexakisphosphate; lithium; Na(+/)myo-inositol transporter; phytate
资金
- NINDS NIH HHS [NS 23831] Funding Source: Medline
Inositol phospholipids and inositol phosphates mediate well-established functions in signal transduction and in Ca2+ homeostasis in the CNS and non-neural tissues. More recently, there has been renewed interest in other roles that both myo -inositol and its highly phosphorylated forms may play in neural function. We review evidence that myo -inositol serves as a clinically relevant osmolyte in the CNS, and that its hexakisphosphate and pyrophosphorylated derivatives may play roles in such diverse cellular functions as DNA repair, nuclear RNA export and synaptic membrane trafficking.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据