期刊
CURRENT OPINION IN CELL BIOLOGY
卷 14, 期 4, 页码 454-462出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/S0955-0674(02)00352-6
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The endosomal system of yeast is simpler than that of animal cells, but as it is mapped more similarities are emerging. A key role for ubiquitin in sorting proteins to and into multivesicular bodies has been demonstrated. The finding that Phox homology domains recognise phosphatidylinositol 3-phosphate explains how sorting nexins are recruited to endosomes, where they mediate the retrieval of membrane proteins from the endocytic pathway.
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