期刊
STATISTICS IN MEDICINE
卷 21, 期 16, 页码 2313-2324出版社
WILEY
DOI: 10.1002/sim.1201
关键词
meta-analysis; mixed model; random effects model; controlled trial
I present methods for assessing the relative effectiveness of two treatments when they have not been compared directly in a randomized trial but have each been compared to other treatments. These network meta-analysis techniques allow estimation of both heterogeneity in the effect of any given treatment and inconsistency ('incoherence') in the evidence from different pairs of treatments. A simple estimation procedure using linear mixed models is given and used in a meta-analysis of treatments for acute myocardial infarction. Copyright (C) 2002 John Wiley Sons, Ltd.
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