期刊
NUTRITIONAL NEUROSCIENCE
卷 5, 期 4, 页码 229-239出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/10284150290028954
关键词
vitamin E; oxidative stress; neurodegenerative disorders; protein oxidation; lipid peroxidation
资金
- NIA NIH HHS [AG-10836, AG-05119] Funding Source: Medline
Several neurodegenerative disorders are associated with oxidative stress that is manifested by lipid peroxidation, protein oxidation and other markers. Included in these disorders in which oxidative stress is thought to play an important role in their pathogenesis are Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS), tardive dyskinesia, Huntington's disease (HD), and multiple sclerosis. This review presents some of the chemistry of vitamin E as an antioxidant and summarizes studies in which vitamin E has been employed in these disorders and models thereof.
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