4.6 Article

Adaptive evolution after gene duplication

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TRENDS IN GENETICS
卷 18, 期 9, 页码 433-434

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ELSEVIER SCIENCE LONDON
DOI: 10.1016/S0168-9525(02)02755-5

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One of the two ribonuclease genes in a leaf-eating monkey has adapted to a role in the digestion of bacterial RNA. Following duplication of the ancestral ribonuclease gene, adaptation occurred through a series of changes in the amino acid sequence of the protein it encodes. This example is a good illustration of how specialization of protein function after gene duplication can be a source of novel protein functions.

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