期刊
BIOPROCESS AND BIOSYSTEMS ENGINEERING
卷 25, 期 3, 页码 165-168出版社
SPRINGER
DOI: 10.1007/s00449-002-0291-z
关键词
Monascus; red pigment; solid-state cultivation; submerged cultivation; adsorptive extraction
A process taking advantages of combined solid-state and submerged cultivation of Monascus for red pigment production and integration of a product removal unit was developed. The solid-state cultivation was carried out in a 5 1 fermentor, with rice being used not only as the substrate but also the support for Monascus. The inclusion of rice submergence and integration of product separation were achieved by intermittently rinsing the rice with monosodium glutamate (MSG) solutions every 12 h followed by an adsorptive extraction of the red pigment dissolved in the rinsing solution. With this new process, the Monascus red pigment production was increased by 24% as compared with that by the plain fixed-bed cultivation.
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