Revision of the American Joint Committee on Cancer staging system for breast cancer

Purpose: To revise the American Joint Committee on Cancer staging system for breast carcinoma. Materials and Methods: A Breast Task Force submitted recommended changes and additions to the existing staging system that were (1) evidence-based and/or consistent with widespread clinical consensus about appropriate diagnostic and treatment standards and (2) useful for the uniform accrual of outcome information in national databases. Results: Major changes included the following: size-based discrimination between micrometastases and isolated tumor cells; identifiers to indicate usage of innovative technical approaches; classification of lymph node status by number of involved axillary lymph nodes, and new classifications for metastasis to the infraclavicular, internal mammary, and supraclavicular lymph nodes. Conclusion: This revised staging system will be officially adopted for use in tumor registries in January 2003. (C) 2002 by American Society of Clinical Oncology.