期刊
ARCHIVES OF ENVIRONMENTAL HEALTH
卷 57, 期 5, 页码 489-495出版社
HELDREF PUBLICATIONS
DOI: 10.1080/00039890209601442
关键词
blood pressure; hypertension in pregnancy; lead; pregnancy; toxemia
资金
- NHLBI NIH HHS [HL-56581] Funding Source: Medline
- NIEHS NIH HHS [ES-07437] Funding Source: Medline
In this study, the authors related blood lead concentrations to Apgar scores, birth weight, gestational age, small-for-gestational age, and hypertension in pregnancy (HIP)/toxemia. Data and blood were collected 4 times during pregnancy from 705 women, aged 12-34 yr. Blood lead concentrations, measured by atomic absorption spectrophotometry, were related to reproductive outcomes, abstracted from medical records. Average blood lead concentrations were 1.2 mug/dl (standard error = +/- 0.03). Maternal blood lead concentrations were related significantly to HIP/toxemia-before and after adjusting for age, calcium intake, and race/ethnicity (p < .03). Longitudinal regression analyses revealed that blood lead concentrations in women with HIP/toxemia changed by 0.02 μg/dl for every 0.01 μg/dl change in women without HIP/toxemia. Maternal blood lead concentration and its change were not significantly associated with other reproductive outcomes. Low levels of maternal blood lead concentrations were significantly associated with HIP/toxemia.
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