期刊
PHYTOCHEMISTRY
卷 61, 期 4, 页码 399-403出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0031-9422(02)00190-5
关键词
Psidium guajava; triterpenoids; guavanoic acid; guavacoumaric acid; spasmolytic activity
Two triterpenoids, 20beta-acetoxy-2alpha,3beta-dihydroxyurs-12-en-28-oic acid (guavanoic acid, 3), and 2alpha,3beta-dihydroxy-24-p-z-coumaroyloxyurs- 12-en-28-oic acid (guavacoumaric acid, 7), along with six known compounds 2alpha-hydroxyursolic acid (1), jacoumaric acid (2), isoneriucoumaric acid (4), asiatic acid (5), ilelatifol D (6) and beta-sitosterol-3-O-beta-D-glucopyranoside (8), have been isolated from the leaves of Psidium guajava. Their structures were determined through spectroscopic methods. Compound 5 showed dose-dependent (10-500 mug/ml) spasmolytic activity in spontaneously contracting isolated rabbit jejunum preparations. (C) 2002 Elsevier Science Ltd. All rights reserved.
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