期刊
TRAFFIC
卷 3, 期 10, 页码 705-709出版社
WILEY
DOI: 10.1034/j.1600-0854.2002.31002.x
关键词
assembly; budding; Ebola; HIV-1; influenza; lipid rafts
类别
The plasma membrane, late secretory pathway and endosomal compartments contain detergent-insoluble raft microdomains that are enriched in sphingolipids and cholesterol. Rafts are currently an intensively studied topic of cell biology, and raft involvement has been implicated in numerous cellular processes. A number of recent reports have localized structural proteins of several enveloped viruses to rafts, thus raising the possibility that rafts also play a role in the assembly and budding of viruses, but what exactly that role might be is still unknown.
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