期刊
SCANDINAVIAN JOURNAL OF RHEUMATOLOGY
卷 31, 期 5, 页码 251-259出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/030097402760375124
关键词
rheumatoid arthritis; hematological; Felty's syndrome
类别
Objective: To inform clinical rheumatologists about the common and rarer hematological manifestations of rheumatoid arthritis with an emphasis on diagnosis and therapy and a particular reference to Felty's syndrome. Methods: Literature review. Results: The hematological manifestations can be conveniently categorized into the broad areas of; anemia, particularly NSAID induced iron deficiency anemia and the anemia of chronic disease; neutropenia, particularly Felty's syndrome and the large granular lymphocyte syndrome and drug induced neutropenia; thrombocytopenia, particularly autoimmune and drug induced thrombocytopenia; and hematological malignancy. Rarer conditions, their diagnosis and therapy are also described in this review. Conclusion: Hematological manifestations of rheumatoid arthritis are very common. A logical approach using easily available tests should allow straightforward decisions about diagnosis and therapy to be made, even in patients with some of the rarer manifestations.
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