期刊
CURRENT OPINION IN STRUCTURAL BIOLOGY
卷 12, 期 5, 页码 628-633出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/S0959-440X(02)00370-6
关键词
-
资金
- NIGMS NIH HHS [GM 35183, GM 53640, P01 GM068036] Funding Source: Medline
There have been recent advances in initiating and perturbing chemical reactions on very fast timescales, as short as picoseconds, thus making it feasible to study a vast range of chemical kinetics problems that heretofore could not be studied. One such approach is the rapid heating of water solutions using laser excitation. Laser-induced temperature jump relaxation spectroscopy can be used to determine the dynamics of protein motion, an area largely unstudied for want of suitable experimental and theoretical probes, despite the obvious importance of dynamics to protein function. Coupled with suitable spectroscopic probes of structure, relaxation spectroscopy can follow the motion of protein atoms over an enormous time range, from picoseconds to minutes (or longer), and with substantial structural specificity.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据