期刊
NEURON
卷 36, 期 2, 页码 265-284出版社
CELL PRESS
DOI: 10.1016/S0896-6273(02)00974-1
关键词
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资金
- NIDA NIH HHS [R01 DA11723, K08 DA00367] Funding Source: Medline
- NIMH NIH HHS [R01 MH61010, R01 MH52797] Funding Source: Medline
A recent flurry of neuroimaging and decision-making experiments in humans, when combined with single-unit data from orbitofrontal cortex, suggests major additions to current models of reward processing. We review these data and models and use them to develop a specific computational relationship between the value of a predictor and the future rewards or punishments that it promises. The resulting computational model, the predictor-valuation model (PVM), is shown to anticipate a class of single-unit neural responses in orbitofrontal and striatal neurons. The model also suggests how neural responses in the orbitofrontal-striatal circuit may support the conversion of disparate types of future rewards into a kind of internal currency, that is, a common scale used to compare the valuation of future behavioral acts or stimuli.
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