Four new Lactones from Botrytis cinerea

Four new lactones (1-4) have been isolated from Botrytis cinerea. Their structures were elucidated by interpretation of spectral data, mainly H-1 and C-13 NMR, including two-dimensional analysis (HOMOCOSY, HMQC, and HMBC). The phytotoxic activities of these new natural products have been evaluated. Compounds 1-3 were inactive, while 4 showed a phytotoxic effect when tested up to 250 ppm.