期刊
MICROBES AND INFECTION
卷 4, 期 13, 页码 1335-1343出版社
EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/S1286-4579(02)00011-4
关键词
listeria monocytogenes; intracellular signaling; macrophage; phospholipase C; protein kinase C
Macrophages are critical for control of Listeria monocytogenes infections; accordingly, the interactions of L. monocytogenes with these cells have been intensively studied. It has become apparent that this facultative intracellular pathogen interacts with macrophages both prior to entry and during the intracellular phase. This review covers recent work on signaling induced in macrophages by L. monocytogenes, especially intracellular signals induced by secreted proteins including listeriolysin O and two distinct phospholipases C. (C) 2002 Editions scientifiques et medicales Elsevier SAS. All rights reserved.
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