期刊
NATURE IMMUNOLOGY
卷 3, 期 11, 页码 1006-1012出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/ni1102-1006
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资金
- NIAID NIH HHS [AI-50207, AI-07512] Funding Source: Medline
- NICHD NIH HHS [F32 HD008515, F32 HD008515-01, F32 HD008515-03, F32 HD008515-02] Funding Source: Medline
Viruses have evolved mechanisms to avoid the host immune system, including means of escaping detection by both the innate and adaptive immune responses. Natural killer (NK) cells are a central component of the innate immune system and are crucial in defense against certain viruses. To attain a state of chronic infection, some successful viruses have developed specific mechanisms to evade detection by and activation of NK cells. These NK cell-specific evasion mechanisms fall into distinct mechanistic categories used in numerous virus families.
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