期刊
BIOORGANIC & MEDICINAL CHEMISTRY
卷 10, 期 11, 页码 3473-3480出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0968-0896(02)00258-4
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A series of diarylamide urea derivatives were synthesized and evaluated for their inhibitory activities against human coronary artery endothelial cells (ECs) and human coronary artery smooth muscle cells (SMCs). Compound 5k was superior to Tranilast, in terms of both cell selectivity and the potency of its inhibitory activity toward the proliferation and angiogenesis of ECs. (C) 2002 Elsevier Science Ltd. All rights reserved.
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