期刊
VETERINARY MICROBIOLOGY
卷 89, 期 4, 页码 255-265出版社
ELSEVIER
DOI: 10.1016/S0378-1135(02)00203-1
关键词
bovine virus; diarrhea virus; vaccination; foetal protection
A protocol is described to measure the protection of the bovine fetus against an experimental bovine virus diarrhea virus (BVDV) infection after vaccination. Two inactivated experimental vaccines were applied twice with a 3 week interval. A mixture of three different Dutch field strains was used as challenge on mainly the 82nd day of gestation to vaccinated and unvaccinated control animals. The challenge was applied 5 months after completion of the two-fold vaccinations. All calves born from unvaccinated control animals were persistently infected. The calves born from dams vaccinated with the two different inactivated BVDV vaccines were persistently infected in 78 and 60%, respectively. (C) 2002 Elsevier Science B.V. All rights reserved.
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