4.5 Article

Multilevel modelling of medical data

期刊

STATISTICS IN MEDICINE
卷 21, 期 21, 页码 3291-3315

出版社

JOHN WILEY & SONS LTD
DOI: 10.1002/sim.1264

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complex data structures; mixed model; multilevel model; random effects model; repeated measures

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This tutorial presents an overview of multilevel or hierarchical data modelling and its applications in medicine. A description of the basic model for nested data is given and it is shown how this can be extended to fit flexible models for repeated measures data and more complex structures involving cross-classifications and multiple membership patterns within the software package MLwiN. A variety of response types are covered and both frequentist and Bayesian estimation methods are described. Copyright (C) 2002 John Wiley Sons, Ltd.

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