期刊
FEBS LETTERS
卷 531, 期 3, 页码 443-447出版社
WILEY
DOI: 10.1016/S0014-5793(02)03581-0
关键词
aquaporin; silver inhibition; gold inhibition; mercury inhibition; nodulin 26; plasma membrane integral protein
Silver and gold compounds were tested as potential inhibitors of aquaporins of plant- and human origin. Silver as AgNO3 or silver sulfadiazine inhibited with high potency (EC50 1-10 muM) the water permeability of the peribacteroid membrane from soybean (containing Nodulin 26), the water permeability of plasma membrane from roots (containing plasma membrane integral proteins), and the water permeability of human red cells (containing aquaporin 1). Gold as HAuCl4 was less effective but still inhibited peribacteroid membrane water permeability (EC50 = 10 muM). Silver and gold are more potent inhibitors of aquaporins than the presently widely used mercury containing compounds. (C) 2002 Federation of European Biochemical Societies. Published by Elsevier Science B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据