期刊
CURRENT OPINION IN GENETICS & DEVELOPMENT
卷 12, 期 6, 页码 664-668出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/S0959-437X(02)00356-8
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Three recent findings are making a deep impact on our understanding of the Drosophila Y. First, the sequencing of the Drosophila genome and the development of proper computational methods increased the number of known single-copy Y-linked genes from 1 to 16, and revealed a chromosome packed with genes acquired from the autosomes. Second, this, coupled with the finding that B-chromosomes are able to show very regular segregation from the X chromosome, reinforce the hypothesis that the Drosophila Y is a specialized B-chromosome, instead of a degenerated homologue of the X. Third and finally, Y chromosomes seem to have a strong effect on male fitness.
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