Pharmacology of synaptic transmission in the enteric nervous system

Recent data indicate that there are multiple mechanisms mediating fast and slow synaptic excitation in the enteric nervous system. However, these data also suggest that both the neurotransmitters and the receptors mediating fast and slow synaptic transmission in the myenteric plexus are organized in a polarity- (ascending versus descending) and pathway- (excitatory versus inhibitory) specific manner.