期刊
BEHAVIORAL MEDICINE
卷 27, 期 4, 页码 141-147出版社
ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD
DOI: 10.1080/08964280209596039
关键词
cardiovascular disease; psychosocial interventions; psychosocial stress; review
资金
- NCCIH NIH HHS [IP50AT00082-01, P50 AT000082-01, P50 AT000082] Funding Source: Medline
- NHLBI NIH HHS [R01 HL073804-04, R01 HL049910-09, HL49910, R01 HL049910, 232HL07380] Funding Source: Medline
The remarkable decline in cardiovascular disease (CVD) experienced in developed countries over the last 40 years appears to have abated. Currently, many CVD patients continue to show cardiac events despite optimal treatment of traditional risk factors. This evidence suggests that additional interventions, particularly those aimed at nontraditional factors, might be useful for continuing the decline. Psychosocial stress is a newly recognized (nontraditional) risk factor that appears to contribute to all recognized mechanisms underlying cardiac events, specifically, (a) clustering of traditional cardiovascular risk factors, (b) endothelial dysfunction, (c) myocardial ischemia, (d) plaque rupture, (e) thrombosis, and (f) malignant arrhythmias. A better understanding of the behavioral and physiologic associations between psychosocial stress and CVD will assist researchers in identifying effective approaches for reducing or reversing the damaging effects of stress and may lead to further reductions of CVD morbidity, and mortality.
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