期刊
MAGNETIC RESONANCE IMAGING
卷 20, 期 10, 页码 743-757出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/S0730-725X(02)00608-2
关键词
MRI; spectroscopic imaging; spiral imaging; truncation artifact reduction; selective reconstruction
资金
- NCRR NIH HHS [RR08079] Funding Source: Medline
- NIMH NIH HHS [R01MH55346] Funding Source: Medline
Truncation artifacts arise in magnetic resonance spectroscopic imaging (MRSI) of the human brain due to limited coverage of k-space necessitated by low SNR of metabolite signal and limited scanning time. In proton MRSI of the head, intense extra-cranial lipid signals bleed into brain regions, thereby contaminating signals of metabolites therein. This work presents a data acquisition strategy for reducing truncation artifact based on extended k-space coverage achieved with a dual-SNR strategy. Using the fact that the SNR in k-space increases monotonically with sampling density, dual-SNR is achieved in an efficient manner with a dual-density spiral k-space trajectory that permits a smooth transition from high density to low density. The technique is demonstrated to be effective in reducing bleeding of extra-cranial lipid signals while preserving the SNR of metabolites in the brain. (C) 2002 Elsevier Science Inc. All rights reserved.
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