期刊
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
卷 12, 期 23, 页码 3475-3478出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0960-894X(02)00703-5
关键词
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Several thiosemicarbazone derivatives of 5-nitrothiophene-2-carboxaldehyde were prepared by the simple process in which N-4-thiosemicarbazone moiety was replaced by aliphatic, arylic and cyclic amine. Among these thiosemicarbazones compound 11 showed significant antiamoebic activity whereas compound 3 was more active antitrichomonal than the reference drug. (C) 2002 Elsevier Science Ltd. All rights reserved.
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