A copper- and amine-free Sonogashira-type coupling procedure catalyzed by oxime palladacycles

Oxime palladacycle derived from 4,4'-dichlorobenzophenone was found to promote the Sonogashira reaction of aryl iodides and aryl bromides with terminal acetylenes using I equivalent of tetrabutylammonium acetate in organic solvents generally in 1 h at 110degreesC and in high TONs (up to 72000). (C) 2002 Elsevier Science Ltd. All rights reserved.