期刊
NEUROREPORT
卷 13, 期 18, 页码 2487-2492出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/00001756-200212200-00022
关键词
alpha rhythm; BOLD; EEG; fMRI; resting state; simultaneous; SITE
资金
- NIDA NIH HHS [R01 DA013054-01, R01 DA 13054-01] Funding Source: Medline
The alpha rhythm in the EEG is 8-12 Hz activity present when a subject is awake with eyes closed. In this study, we used simultaneous EEG and fMRI to make maps of regions whose MRI signal changed reliably with modulation in posterior alpha activity. We scanned II subjects as they rested with eyes closed. We found that increased alpha power was correlated with decreased MRI signal in multiple regions of occipital, superior temporal, inferior frontal, and cingulate cortex, and with increased signal in the thalamus and insula. These results are consistent with animal experiments and point to the alpha rhythm as an index of cortical inactivity that may be generated in part by the thalamus. These results also may have important implications for interpretation of resting baseline in fMRI studies.
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