期刊
CHEMPHYSCHEM
卷 4, 期 1, 页码 14-30出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/cphc.200390004
关键词
confocal microscopy; life sciences; Raman spectroscopy; SERS; vibrational spectroscopy
Although the physics of Raman spectroscopy and its application to purely chemical problems is long established, it offers a non-invasive, nondestructive, and water-insensitive probe to problems in the life sciences. Starting from the principles of Raman spectroscopy, its advantages, and methods for signal enhancement, the bulk of the review highlights recent applications. Structural investigations of a hormone receptor, testing the biocompatibility of dental implants, probing soil components and plant tissue alkaloids, and localization of single bacteria are just four problems in which Raman spectroscopy offers a solution of complements existing methods.
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