期刊
JOURNAL OF CELL SCIENCE
卷 116, 期 2, 页码 211-216出版社
COMPANY BIOLOGISTS LTD
DOI: 10.1242/jcs.00248
关键词
nuclear migration; nuclear anchorage; UNC-84; SUN domain; ANG-1; muscular dystrophy; nuclear envelope
类别
资金
- NIGMS NIH HHS [F32 GM020127] Funding Source: Medline
Mechanisms for nuclear migration and nuclear anchorage function together to control nuclear positioning. Both tubulin and actin networks play important roles in nuclear positioning. The actin cytoskeleton. has been shown to position nuclei in a variety of systems from yeast to plants and animals. It can either act as a stable skeleton to anchor nuclei or supply the active force to move nuclei. Two C elegans genes and their homologues play important roles in these processes. Syne/ANC-1 anchors nuclei by directly tethering the nuclear envelope to the actin cytoskeleton, and UNC-84/SUN functions at the nuclear envelope to recruit Syne/ANC-1.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据