期刊
EXPERIMENTAL AND CLINICAL PSYCHOPHARMACOLOGY
卷 11, 期 1, 页码 91-101出版社
AMER PSYCHOLOGICAL ASSOC
DOI: 10.1037/1064-1297.11.1.91
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Variations in affect following d-amphetamine and placebo were examined in healthy young adults who subsequently preferred d-amphetamine (choosers; n = 61) or placebo (nonchoosers; n = 48) in a drug preference procedure. Affect was assessed before and 1, 3, and 6 hr after participants received the placebo and 10 mg d-amphetamine. Following amphetamine as compared with placebo, choosers' ratings increased on scales measuring energy, cognitive efficiency, and well-being, and decreased on scales measuring fatigue and sedation. Non-choosers reported no effects, sedative effects, and dysphoric effects of amphetamine. Following placebo, ratings of energy, efficiency, and well-being decreased, and ratings of sedation increased in choosers but not in nonchoosers. Variations in affect following placebo and amphetamine may constitute markers of risk for drug use.
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