期刊
NETWORK-COMPUTATION IN NEURAL SYSTEMS
卷 14, 期 1, 页码 5-15出版社
TAYLOR & FRANCIS INC
DOI: 10.1088/0954-898X/14/1/301
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The purpose of smoothing (filtering) neuronal data is to improve the estimation of the instantaneous firing rate. In some applications, scientific interest centres on functions of the instantaneous firing rate, such as the time at which the maximal firing rate occurs or the rate of increase of firing rate over some experimentally relevant period. In others, the instantaneous firing rate is needed for probability-based calculations. In this paper we point to the very substantial gains in statistical efficiency froth smoothing methods compared to using the peristimulus-time histogram (PSTH), and we also demonstrate a new method of adaptive smoothing known as Bayesian adaptive regression splines (DiMatteo I, Genovese C R and Kass R E 2001 Biometrika 88 1055-71). We briefly review additional applications of smoothing with non-Poisson processes and in the joint PSTH for a pair of neurons.
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