期刊
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
卷 47, 期 2, 页码 783-785出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.47.2.783-785.2003
关键词
-
资金
- NIAID NIH HHS [N01AI95385] Funding Source: Medline
We have developed a rapid new in vivo method for screening experimental drugs for their activity against Mycobacterium tuberculosis by using the gamma interferon gene-disrupted (GKO) C57BL/6 mouse. Due to the rapid growth of the infection, statistical differences indicating positive efficacy of active compounds can be seen after only 8 days of treatment. To validate this model, several fluoroquinolones, including ciprofloxacin, levofloxacin, moxifloxacin, and gatifloxacin, were tested in parallel.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据