期刊
BRITISH JOURNAL OF HAEMATOLOGY
卷 120, 期 4, 页码 691-694出版社
BLACKWELL PUBLISHING LTD
DOI: 10.1046/j.1365-2141.2003.04125.x
关键词
CD2 expression; mast cells; systemic mast cell disease
类别
Recently, aberrant coexpression of CD2 and CD25 has been reported to reliably distinguish neoplastic mast cells from normal or so-called reactive mast cells. Such expression is included in the consensus diagnostic criteria for systemic mast cell disease (SMCD). In our study of patients with SMCD, we found CD2 expression to be more prevalent on mast cells from patients without an associated haematological disorder (P = 0.04). Furthermore, no correlation was found between mast cell CD2 expression and other clinicopathological features in these patients.
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