期刊
REVISTA DE SAUDE PUBLICA
卷 37, 期 1, 页码 107-115出版社
REVISTA DE SAUDE PUBLICA
DOI: 10.1590/S0034-89102003000100016
关键词
Chagas' disease; Trypanosoma cruzi; xenodiagnosis; polymerase chain reaction
Although there has been an improvement in the diagnosis of chronic Chagas' disease, the low sensitivity of indirect parasitological tests is a drawback to its application in diagnosis and post-therapeutic control. Polymerase chain reaction (PCR) has limited use in routine diagnosis due to the need of specific laboratory,facilities, common DNA cross-contamination, and high costs. At the same time, the high variability of PCR results found in different regions of Brazil raises some questions concerning its applicability. for diagnosis. PCR high specificity is indicative that it can be used as a confirmation method in inconclusive serology diagnosis as well as an auxiliarly method in pos-therapeutic control of chronic Chagas' disease when comparing to serology and parasitological techniques. It is discussed here the applicability of molecular and indirect parasitological methods in the diagnosis and post-therapeutic control of chronic Chagas' disease based on the literature published from 1954 to 2001.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据