期刊
INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY
卷 292, 期 7-8, 页码 541-545出版社
URBAN & FISCHER VERLAG
DOI: 10.1078/1438-4221-00225
关键词
Staphylococcus aureus; exfoliative toxins; PFGE; PCR; ribotyping; prophages
Genotyping of sixteen exfoliative toxin-producing (ET-positive) strains of Staphylococcus aureus isolated in maternity units of two distant hospitals was accomplished by PFGE, ribotyping, PCR ribotyping, and prophage carriage. Three strains secreted combined ETA+ ETB, and the remaining produced ETA and enterotoxin C, or TSST-1. The comparison of various genomic profiles resulted in the identification of nine genotypes. The presence of one prevailing genotype was demonstrated in each hospital. Evidence was given that the outbreak-related ET-positive strains causing the skin disease pemphigus neonatorum disseminated in both the hospitals did not originate from a single source or a common ancestor.
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