期刊
CURRENT OPINION IN NEUROLOGY
卷 16, 期 1, 页码 35-43出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/00019052-200302000-00005
关键词
chronic progressive external ophthalmoplegia; cortical blindness; homonymous hemianopia; Leber's hereditary optic neuropathy; mitochondrial disease; mitochondrial encephalomyopathy; lactic acidosis; and stroke-like episodes; ophthalmoplegia; optic neuropathy; pigmentary retinopathy
资金
- NEI NIH HHS [P30-EY06360] Funding Source: Medline
The afferent and efferent visual pathways within the central nervous system are frequently involved in mitochondrial diseases. Neuro-ophthalmic signs figure prominently and may be the presenting or even sole manifestation of these disorders. The four most common neuro-ophthalmic abnormalities seen in mitochondrial disorders are bilateral optic neuropathy, ophthalmoplegia with ptosis, pigmentary retinopathy, and retrochiasmal visual loss.
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