The Kin I kinesins are microtubule end-stimulated ATPases

The Kin I kinesins are microtubule-destabilizing enzymes important for neuronal transport, spindle assembly, and chromosome segregation. Hunter et al. (2003) now show that the Kin I MCAK is a microtubule end-stimulated ATPase that can catalytically depolymerize MT's.