期刊
BIOINFORMATICS
卷 19, 期 3, 页码 429-430出版社
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btg006
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We have developed a program for automatic identification of domains in protein three-dimensional structures. Performance of the program was assessed by three different benchmarks: (i) by comparison with the expert-curated SCOP database of structural domains; (ii) by comparison with a collection of manual domain assignments; and (iii) by comparison with a set of 55 proteins, frequently used as a benchmark for automatic domain assignment. In all these benchmarks PDP identified domains correctly in more than 80% of proteins.
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