期刊
VACCINE
卷 21, 期 9-10, 页码 921-924出版社
ELSEVIER SCI LTD
DOI: 10.1016/S0264-410X(02)00541-8
关键词
IRIVs; liposomal; immune response
Immunostimulating reconstituted influenza virosomes (IRIVs) are a liposomal carrier system. Influenza hemagglutinin and neuraminidase are intercalated into the lipid bilayer and give the IRIVs their fusogenic activity. The system is already registered for human use and allows a specific targetting of antigens to a cellular or a humoral immune response. IRIVs are able to deliver proteins, RNA/DNA, peptides and mimetics to immunocompetent cells.
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