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Tandem cross-metathesis/hydrogenation/cyclization reactions by using compatible catalysts

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ORGANIC LETTERS
卷 5, 期 4, 页码 459-462

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AMER CHEMICAL SOC
DOI: 10.1021/ol027347m

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[GRAPHICS] A one-pot tandem cross-metathesis/hydrogenation/cyclization procedure was achieved at room temperature, under 1 atm of hydrogen, in the presence of a ruthenium catalyst and PtO2 showing the compatibility of the two catalysts. This tandem reaction allows the synthesis of substituted lactones and lactols from acrylic acid and acrolein, respectively, in the presence of unsaturated alcohols.

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